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senorjosh.comprojects (recent)
10 over 100
November 11, 2005
it'd make me happy if you guys all checked out 10 over 100, a website i've been working on pretty furiously these past few weeks. i think it's one of the better things i've done with myself so far, and if you like what you see tell your friends! ... and for now, just ignore that I haven't posted in 13 months :)
Posted by senorjosh at 02:29 AM | Comments (0) | TrackBack (0)
the big issue
March 31, 2004
The Cape Town wing of The Big Issue just published one of my articles in their April edition. Here's the leader...

Many are the prophets of the Information Age. They preach the wonders of technology, of “information at your fingertips.” Soon, we are told, the Internet will usher in a new era of global connectivity and human understanding. Soon, computers will cure our diseases and do our dishes. But 'soon' means different things in different countries.



Posted by senorjosh at 02:20 AM | Comments (1) | TrackBack (0)
OneWorld TV documentary
December 2, 2003
Wizzy Digital Courier provides offline Internet to African schools. Using a camera provided by bridges.org, I spent the past few days making a short video documentary of the project. If you have RealPlayer installed, you can view the documentary (a series of five 90-second clips), at


students_computers.jpg

More information on the initiative can be found in the this article, or at the Wizzy Digital Courier website. The trip to Khayelitsha is described in my journal entry site b.


Posted by senorjosh at 07:53 AM | Comments (2) | TrackBack (0)
first quarterly report
October 26, 2003
submitted to the watson foundation 10/29/03

“What is the point of the Watson Fellowship?”

I hate that question. Everyone asks; everyone gets a different answer. The truth is, I don’t think a good answer exists. No answer is the right combination of informative and vague. Yes, I am here to learn – but what about? About the digital divide, about other cultures, about adversity and ingenuity, or just “about myself”? All of the above, I know. However, in deciding how to spend my time, all of the above do not always point in the same direction. So far, my biggest “progress, difficulties and triumphs” have been in deciding what to do with myself, and in deciding what I want to get out of the fellowship.

Continue reading "first quarterly report"

Posted by senorjosh at 05:47 PM | Comments (3) | TrackBack (0)
IMSA paper published
October 18, 2003
The team at Microsoft, with whom I worked last summer, just published a paper on the work we did, and were kind enough to include me as a co-author. The full citation is:

Gemmell, Jim, Lueder, Roger, Blumenstock, Joshua, Solomon, Evan and Bell, Gordon. Telephone, Television and Radio in the Home of the Future Internet and Multimedia Systems and Applications (IMSA) 2003, August 13-15, 2003, Honolulu, Hawaii, USA.

Abstract

The home of the future will have an all-digital network for all media, backed by multi-terabyte storage. Users will be able keep an entire lifetime of personal media, and vast collections of media that may be of interest for future viewing, reading, or listening. MyLifeBits is a personal store for a digital life, designed to support efficient organization, search, browsing, annotation, and viewing. This paper describes the telephone, television, and radio components of the MyLifeBits system.

You can download the paper here: Word (2.5MB)  PDF (1.7MB)


Posted by senorjosh at 09:43 PM | Comments (0) | TrackBack (0)
JNCI paper published
June 26, 2003
Gavin J. Gordon, Roderick V. Jensen, Li-Li Hsiao, Steven R. Gullans, Joshua E. Blumenstock, William G. Richards, Michael T. Jaklitsch, David J. Sugarbaker, and Raphael Bueno. Using Gene Expression Ratios to Predict Outcome Among Patients With Mesothelioma Journal of the National Cancer Institute 95:8 (Apr. 2003): 598-605

Abstract

We have recently demonstrated that simple ratios of the expression levels of selected genes in tumor samples can be used to distinguish among types of thoracic malignancies. We examined whether this technique could predict treatment-related outcome for patients with mesothelioma. Methods: We used gene expression profiling data previously collected from 17 mesothelioma patients with different overall survival times to define two outcome-related groups of patients and to train an expression ratio-based outcome predictor model. A Student’s t test was used to identify genes among the two outcome groups that had statistically significant, inversely correlated expression levels; those genes were used to form prognostic expression ratios. We used a combination of several highly accurate expression ratios and cross-validation techniques to assess the internal consistency of this predictor model, quantitative reverse transcription–polymerase chain reaction of tumor RNA to confirm the microarray data, and Kaplan–Meier survival analysis to validate the model among an independent set of 29 mesothelioma tumors. All statistical tests were two-sided. Results: We developed an expression ratio-based test capable of identifying 100% (17/17) of the samples used to train the model. This test remained highly accurate (88%, 15/17) after cross-validation. A four-gene expression ratio test statistically significantly (P = .0035) predicted treatment-related patient outcome in mesothelioma independent of the histologic subtype of the tumor. Conclusions: Gene expression ratio-based analysis accurately predicts treatment-related outcome in mesothelioma samples. This technique could impact the clinical treatment of mesothelioma by allowing the preoperative identification of patients with widely divergent prognoses.


Posted by senorjosh at 09:48 PM | Comments (0) | TrackBack (0)
Putting cancer on the run
June 6, 2003
E. Coli causes diarrhea, and may fight cancer as well

MANY a stalwart man trembles at the mention of the word “colonoscopy.” Odysseus braved Hades and defied the dreaded Scylla, but never did he confront the neighborhood proctologist. Yet colorectal cancer, the fourth leading cause of cancer worldwide, claims tens of thousands of lives each year, and is not a disease easily wiped aside. Maybe, suggests Dr. GianMario Pitari of Thomas Jefferson University, we can flush it out.

Continue reading "Putting cancer on the run"

Posted by senorjosh at 12:31 PM | Comments (0)
music of my mind (short story)
May 30, 2003
Sailing in seizures of laughter, crawling out from under the heel of love, tearing down a dirt road away from Salvador, the bus shakes and I can't sleep. I'm exhausted, just want to drift away, but as my head bounces against the window all I can think is Paul Simon. Paul Simon, Stevie Wonder, Al Green, they fill my aches with words and sighs with song. Here, on the bus, the lyrics seem out of place. But so am I, and why censor? Paul was right: some stories are magical, meant to be sung. This is what filled my head then and now; this is the story of how I begin to remember...
read more...
Posted by senorjosh at 01:12 AM | Comments (1)
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